The Markster replied: "Yup! Sounds like Herxheimer reaction to ME. The abx you've been starting on can initaite a die-off the disseminated Lyme, causing ALL the symptoms that you mentioned. {I had 3 out of the 4 of those the 1st month I was on meds for my Lyme.} The thing that stands out is you HAD the typical bullseye rash, which means you were nearly certain to have been infected with the Lyme borrellia. After a year, they are disseminated throughout the body where they might not cause problems if your immune system is keeping them in "check". Or...odd pains may pop up here & there, possibly along with a feeling of being tired overall... atleast more than you were before the bullseye ring. HAVE your THYROID TESTED! (TSH level, etc.) It's often affected by this bug. Any doc familiar w/ the disease knows that 30 days of dyoxy at this stage in NO WAY will be the cure- or even the proper treatment. Dyoxy is bacteriostatic in that it doesn't actually lyse (kill) the spirochettes directly but impedes them so that they die out by interfering with their 'growth phase', which- for Lyme bacteria- happens only once every 28 days!!. It really sounds like you need to discuss all this with a Lyme-literate doc (often referred to as an LLMD) so he/ she can take in your whole history/ all med reactions & current symptomology and combine that with bloodwork run at a GOOD lab, looking for evidence of active Lyme infection. Then they can get you on a proper antibiotic program, which is often altered after a few months to attack the bugs from a "different angle." I was fine with a few meds (like dyoxy & Biaxin) in the years BEFORE I got Lyme, reacted strongly/ poorly to them after I was infected & tested + , but can now take them again w/o issue. This is a common story. But follow the doc's instructions carefully. You don't want to dive into the abx too quickly. That can result in major "herxing" & you'll end up in the E.R! (where they won't really be able to do much for ya ANY-way.) If you ARE diagnosed w/ 'late-stage Lyme', you'll need to be on abx for several MONTHS. The GOOD news is that the herxing will get less & less (it usually comes in waves) over the many weeks, until the 'ketes are knocked so far down that you'll be feeling better than you've had for a lo-o-ong time. As far as a M.V.Prolapse, that can account for an occasional heartbeat irregularity, but it doesn't cause that chest pain, rapid heartbeat OR high blood pressure. THAT might very well be a "battle"going on inside you & you DON'T want to "withdraw" early! That's how you end up w/ antibiotic-resistant strains of bugs. Good LUCK!"