sparkynugget84 replied: "Basic Information
Metronidazole is an antibiotic which is commonly used to treat protozoal infections and anaerobic bacterial infections. It also has anti-inflammatory effects in the bowel. Metronidazole is bactericidal; it kills bacterial microorganisms by disrupting their DNA. It is rapidly absorbed from the GI tract, metabolized by the liver and excreted in the urine and the feces. Because metronidazole only has activity against anaerobic bacteria, it is commonly used with other antibiotics when it is used to treat mixed bacterial infections. It is compatible with many other antibiotics including penicillin antibiotics, aminoglycosides, and some cephalosporins.
Dogs and Cats
Metronidazole is used to treat protozoal infections in cats and dogs including Giardia, Entamoeba, Trichomonas, and Balantidium. It is also used to treat anaerobic bacterial infections. Metronidazole has immune modulating activity and may be prescribed to treat inflammatory bowel disease. It may be used to treat colitis caused by other antibiotics, periodontal disease (especially in cats), Clostridium perfringens enterotoxemia, tetanus, diarrhea of undetermined cause, pancreatic insufficiency (with small intestinal bacterial overgrowth), and complications of severe liver disease. Metronidazole may be used with corticosteroids in the treatment of inflammatory bowel disease, or gum disease (gingivitis/stomatitis) in cats. Topical metronidazole gel is used in the treatment of skin infections, such as feline chin acne.
Metronidazole is usually tolerated better if given with food and there are a wide variety of flavors and preparations made by
compounding pharmacies in order to deal with the problems associated with the bitter taste. Because of the variety of uses for this drug, dose amount, frequency and duration of treatment vary widely.
Side Effects
• Most common: clinical signs related to the bad taste, or GI upset.
• Dogs and cats: excessive salivation, gagging, regurgitation, pawing at the mouth, nausea, vomiting, and decreased appetite are the most frequent complaints. Less common or rare side effects include diarrhea, depression, lethargy, weakness, low white blood cell count, liver failure, and blood in the urine, or dark urine due to pigment changes. Neurologic signs may be seen after accidental overdose or, more commonly, with long-term moderate to high-dose therapy as in the treatment of difficult bacterial infections. Signs often begin 7 to 12 days following the start of treatment.
• Horses: side effects are not commonly associated with metronidazole. The major problem with using this drug is its bad taste. Many horses stop eating when this drug is mixed with feed and a reliable method of administration must be found.
Precautions
• Metronidazole causes birth defects in laboratory animals. It should be avoided in pregnant animals, especially in the first trimester. Some metronidazole is excreted in breast milk, and it should not be used in lactating animals.
• Metronidazole should not be used in young puppies and kittens.
• Metronidazole should be avoided or used with caution, at reduced doses, in animals with kidney or liver disease.
Drug Interactions
• Metronidazole is reported to elevate prothrombin time in animals on warfarin or other coumarin anticoagulants.
• Cimetidine can interfere with the liver's ability to break down metronidazole and the dose may have to be reduced.
• Phenobarbital and phenytoin may increase the metabolism of metronidazole.
Overdose
• Dogs and cats: Symptoms of overdose of metronidazole include the gastrointestinal signs (anorexia, vomiting) and neurologic signs including depression, ataxia, disorientation, head-tilt, tremors, bradycardia, rigidity, stiffness, and seizures. Neurologic signs may occur due to acute overdose although they are more commonly seen in animals that are on long-term moderate or high doses (oral doses greater than 66 mg/kg/day). Signs of chronic toxicity often begin 7-12 days following the start of treatment. After the drug is discontinued, it may be several days to two weeks before these neurologic signs begin to diminish."
I had clymadia. I took the azrim 250mg 4 pills and its been two days and still have itching? will it go away? So now i supposely have a bacteria infection and have been taking metronidazole and nitrofurantoin. i had stop taking the metro for awhile and now only have 3 pills left will that affect me??????? ergh i just want the pain to go away. im soo sick of this crap
mywatchisslow replied: "sounds weird, but take a salt bath (even regular table salt will do).
will take away the itching quick. honest.
eat a few yogurts a day to balance you out. give it a shot.
For the rest you need to see your doc, sorry your having such a rough time."
monicalei replied: "Did you finish all your pills? you said you stopped taking the metro.
You can't stop taking antibiotics because the bacteria that survive will just replicate again and you won't get better. worse, the bacteria that return may be resistant to the antibiotic that you stopped taking. That is why you ALWAYS have to COMPLETE ALL your antibiotics.
Also, did you have sex with the same person who gave you chlamydia in the first place. was he/she treated? You both have to finish your meds and wait one week before you have sex again. otherwise you will reinfect one another."
Tiare replied: "the itching is not from the chlamydia, it is from the bacterial infection. If you stopped your metronidazole and did not take as directed, you have an excellent chance of still having the infection. It has a tendency to recur or not be treated if you dont take the meds for the full week as directed. See your doctor, you may need another course of metronidazole. Take it the way you are suppossed to for the full 7 days and that should do the trick"
Mary L replied: "YOU NEED TO GO BACK TO THE DOCTOR ."
my doctor gave me treatment for h pylory clarithromycin ,metronidazole,omeprazol is it correct? my bw showed hpylory positive and my doc gave me flagyl 250mg bid ,omeprazol 20mg 2bid and clarithromycin 250mg 2bid .is it correct treatment ,there are two antibiotic together? thank you
thejoker8301 replied: "Im pretty sure the doctor knows what he's doing....all the medications will work together to clear up the infection....and you have one antibiotic, one antifungal, and one stomach medication....not two antibiotics....make sure you do NOT take alcohol while taking that flagyl (metronidazole)....Im very serious!!
Any other questions you have you should refer to the pharmacist you picked up your medications from...."
matador89 replied: "mnslmax3399,
You appear to be on what might be termed as ‘correct’ treatment. Why you did not question your doctor and ask for an explanation instead of coming to a forum, where you have no guarantee of authenticity of answers, is beyond me. Over the past decade many different therapies were promoted and recommendations changed rapidly. Most doctors lost track, and a great variety of treatments are being used. Doctors should choose two complementary regimens, which if used consecutively come close to a 100% cure. Treatment should start with a regimen based on clarithromycin with a back up regimen based on metronidazole unless resistance is above 15%, in which case the order should be reversed. Triple regimens which combine clarithromycin and metronidazole should not be used as there is no valid empirical back up regimen after failure. Dual treatments combining a proton pump inhibitor with either amoxicillin or clarithromycin were popular a few years ago as they were easy to explain and well tolerated. They have now been abandoned because they were not very effective. The newer regimen of 14 days' treatment with ranitidine bismuth citrate plus clarithromycin is effective and has few side effects. In randomised trials it was superior to other dual treatments. It is easy to take and therefore attractive for general practice. Bismuth triple therapy has mainly been surpassed by seven day triple regimens using proton pump inhibitors; these combine omeprazole, lansoprazole, or pantoprazole with two antibiotics. Most studies use the antibiotics twice daily. There is some evidence that the optimal dose is 20 mg twice daily for omeprazole, 30 mg twice daily for lansoprazole, and 40 mg twice daily for pantoprazole. The appropriate antibiotics are metronidazole (or tinidazole), amoxicillin, and clarithromycin. Several guidelines recommend proton pump inhibitor triple regimens as first line treatment. Proton pump inhibitors are most commonly combined with amoxicillin 1000 mg twice daily and clarithromycin 500 mg twice daily. This regimen has fewer side effects then other triple regimens, but it is only moderately effective in clarithromycin resistant strains and secondary resistance is usually induced when treatment fails.
I add a link with details of this subject.
ALL ANSWERS SHOULD BE THOROUGHLY RESEARCHED, IN ANY FORUM AND ESPECIALLY IN THIS ONE. MANY ANSWERS ARE FLAWED.
The information provided here should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions.
Comparison/NewComparison/
0,10621,550540-21,00.html
Hope this helps
matador 89"

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